LECT2 Amyloidosis (ALECT2) and The REFLECTION ALECT2 Natural History Study

Find out if you may qualify for the REFLECTION ALECT2 study.

For people living with LECT2 amyloidosis (ALECT2), disease knowledge and current treatment options are limited. The REFLECTION natural history study is gathering information to increase understanding of ALECT2 and, we hope, inform the development of future treatment options for people with the condition.

Renal Amyloidosis

Renal amyloidosis occurs when abnormally folded proteins form fibrous deposits, called ‘amyloid’ in the kidneys. Learn more about different types of renal amyloidosis.

About LECT2 Amyloidosis (ALECT2)

ALECT2 is a recently identified form of renal amyloidosis, and the subject of the REFLECTION natural history study. Learn more, including what to ask your doctor if you think you might have ALECT2.

ALECT2 study

REFLECTION is a “natural history” study designed to gather information about ALECT2, a form of renal amyloidosis that can, over a number of years, ultimately result in kidney failure.

ALECT2 Information for Healthcare Providers

Leukocyte Chemotactic Factor 2 Amyloidosis, or ALECT2, is a newly described form of systemic amyloidosis, clinically implicated as a cause of slowly progressive chronic kidney disease (CKD) occurring in adults.

Find out if you qualify for the REFLECTION study